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The mechanism by which chlortalidone reduces blood pressure is not fully known but may be related to the excretion and redistribution of body sodium. This occurs when the kup tenoretic cheap puylse becomes slow and an extra beat is initiated by the heart. The use of chlorthalidone and related drugs in pregnant women requires that the anticipated benefits of the drug be weighed against possible hazards to the fetus. Abrupt withdrawal of beta blockade might precipitate thyroid therefore, patients suspected of developing thyrotoxicosis from whom TENORETIC therapy is to be withdrawn should be monitored closely. The second condition is that the material is not to be used for any purpose contrary to the purposes and objectives of this site. Premature infants, or infants with impaired renal function, may be more likely to develop adverse effects. Hypokalemia can sensitize or exaggerate the response of the heart to the toxic effects of digitalis eg, increased ventricular irritability.

 
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